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CHUK/IKK-α loss in lung epithelial cells enhances NSCLC growth associated with HIF up-regulation
Through the progressive accumulation of genetic and epigenetic alterations in cellular physiology, non–small-cell lung cancer (NSCLC) evolves in distinct steps involving mutually exclusive oncogenic mutations in K-Ras or EGFR along with inactivating mutations in the p53 tumor suppressor. Herein, we...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892436/ https://www.ncbi.nlm.nih.gov/pubmed/31792060 http://dx.doi.org/10.26508/lsa.201900460 |