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TspanC8 tetraspanins differentially regulate ADAM10 endocytosis and half-life

ADAM10 is a transmembrane metalloprotease that is essential for development and tissue homeostasis. It cleaves the ectodomain of many proteins, including amyloid precursor protein, and plays an essential role in Notch signaling. ADAM10 associates with six members of the tetraspanin superfamily refer...

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Detalles Bibliográficos
Autores principales: Eschenbrenner, Etienne, Jouannet, Stéphanie, Clay, Denis, Chaker, Joëlle, Boucheix, Claude, Brou, Christel, Tomlinson, Michael G, Charrin, Stéphanie, Rubinstein, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892437/
https://www.ncbi.nlm.nih.gov/pubmed/31792032
http://dx.doi.org/10.26508/lsa.201900444