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Type I interferon limits mast cell–mediated anaphylaxis by controlling secretory granule homeostasis
Type I interferon (IFN-I) is a family of multifunctional cytokines that modulate the innate and adaptive immunity and are used to treat mastocytosis. Although IFN-I is known to suppress mast cell function, including histamine release, the mechanisms behind its effects on mast cells have been poorly...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892554/ https://www.ncbi.nlm.nih.gov/pubmed/31730616 http://dx.doi.org/10.1371/journal.pbio.3000530 |