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Type I interferon limits mast cell–mediated anaphylaxis by controlling secretory granule homeostasis

Type I interferon (IFN-I) is a family of multifunctional cytokines that modulate the innate and adaptive immunity and are used to treat mastocytosis. Although IFN-I is known to suppress mast cell function, including histamine release, the mechanisms behind its effects on mast cells have been poorly...

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Detalles Bibliográficos
Autores principales: Kobayashi, Toshihiko, Shimabukuro-Demoto, Shiho, Tsutsui, Hidemitsu, Toyama-Sorimachi, Noriko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892554/
https://www.ncbi.nlm.nih.gov/pubmed/31730616
http://dx.doi.org/10.1371/journal.pbio.3000530