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Spatiotemporal constraints on optogenetic inactivation in cortical circuits

Optogenetics allows manipulations of genetically and spatially defined neuronal populations with excellent temporal control. However, neurons are coupled with other neurons over multiple length scales, and the effects of localized manipulations thus spread beyond the targeted neurons. We benchmarked...

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Detalles Bibliográficos
Autores principales: Li, Nuo, Chen, Susu, Guo, Zengcai V, Chen, Han, Huo, Yan, Inagaki, Hidehiko K, Chen, Guang, Davis, Courtney, Hansel, David, Guo, Caiying, Svoboda, Karel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892606/
https://www.ncbi.nlm.nih.gov/pubmed/31736463
http://dx.doi.org/10.7554/eLife.48622