Glioblastoma Model Using Human Cerebral Organoids

We have developed a cancer model of gliomas in human cerebral organoids that allows direct observation of tumor initiation as well as continuous microscopic observations. We used CRISPR/Cas9 technology to target an HRas(G12V)-IRES-tdTomato construct by homologous recombination into the TP53 locus. R...

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Detalles Bibliográficos
Autores principales: Ogawa, Junko, Pao, Gerald M., Shokhirev, Maxim N., Verma, Inder M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892608/
https://www.ncbi.nlm.nih.gov/pubmed/29694897
http://dx.doi.org/10.1016/j.celrep.2018.03.105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892608/
https://www.ncbi.nlm.nih.gov/pubmed/29694897
http://dx.doi.org/10.1016/j.celrep.2018.03.105

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