Rare variants contribute disproportionately to quantitative trait variation in yeast

How variants with different frequencies contribute to trait variation is a central question in genetics. We use a unique model system to disentangle the contributions of common and rare variants to quantitative traits. We generated ~14,000 progeny from crosses among 16 diverse yeast strains and iden...

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Detalles Bibliográficos
Autores principales: Bloom, Joshua S, Boocock, James, Treusch, Sebastian, Sadhu, Meru J, Day, Laura, Oates-Barker, Holly, Kruglyak, Leonid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892613/
https://www.ncbi.nlm.nih.gov/pubmed/31647408
http://dx.doi.org/10.7554/eLife.49212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892613/
https://www.ncbi.nlm.nih.gov/pubmed/31647408
http://dx.doi.org/10.7554/eLife.49212

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