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A cost-effectiveness model of genetic testing and periodical clinical screening for the evaluation of families with dilated cardiomyopathy

PURPOSE: To assess the relative cost-effectiveness of cascade genetic testing in asymptomatic relatives of patients with dilated cardiomyopathy (DCM) compared with periodical clinical surveillance. METHODS: A decision-analytic model, combining a decision tree and a Markov model, was used to determin...

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Detalles Bibliográficos
Autores principales: Catchpool, Max, Ramchand, Jay, Martyn, Melissa, Hare, David L., James, Paul A., Trainer, Alison H., Knight, Josh, Goranitis, Ilias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892743/
https://www.ncbi.nlm.nih.gov/pubmed/31222143
http://dx.doi.org/10.1038/s41436-019-0582-2