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Aptamer-modified gold nanoparticles for rapid aggregation-based detection of inflammation: an optical assay for interleukin-6

A proof-of-concept aptamer-based optical assay is described for the determination of the immuno signalling molecule interleukin-6 (IL-6), a key marker of acute inflammation. The optical assay is based on the aggregation of gold nanoparticles (AuNP) coated in two complimentary “sandwich-style” aptame...

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Detalles Bibliográficos
Autores principales: Giorgi-Coll, Susan, Marín, María J., Sule, Olajumoke, Hutchinson, Peter J., Carpenter, Keri L.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892788/
https://www.ncbi.nlm.nih.gov/pubmed/31802241
http://dx.doi.org/10.1007/s00604-019-3975-7