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Novel genome-wide associations for anhedonia, genetic correlation with psychiatric disorders, and polygenic association with brain structure

Anhedonia is a core symptom of several psychiatric disorders but its biological underpinnings are poorly understood. We performed a genome-wide association study of state anhedonia in 375,275 UK Biobank participants and assessed for genetic correlation between anhedonia and neuropsychiatric conditio...

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Detalles Bibliográficos
Autores principales: Ward, Joey, Lyall, Laura M., Bethlehem, Richard A. I., Ferguson, Amy, Strawbridge, Rona J., Lyall, Donald M., Cullen, Breda, Graham, Nicholas, Johnston, Keira J. A., Bailey, Mark E. S., Murray, Graham K., Smith, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892870/
https://www.ncbi.nlm.nih.gov/pubmed/31797917
http://dx.doi.org/10.1038/s41398-019-0635-y