Synthetic chimeric nucleases function for efficient genome editing

CRISPR–Cas systems have revolutionized genome editing across a broad range of biotechnological endeavors. Many CRISPR-Cas nucleases have been identified and engineered for improved capabilities. Given the modular structure of such enzymes, we hypothesized that engineering chimeric sequences would ge...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, R. M., Liang, L. L., Freed, E., Chang, H., Oh, E., Liu, Z. Y., Garst, A., Eckert, C. A., Gill, R. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892893/
https://www.ncbi.nlm.nih.gov/pubmed/31797930
http://dx.doi.org/10.1038/s41467-019-13500-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892893/
https://www.ncbi.nlm.nih.gov/pubmed/31797930
http://dx.doi.org/10.1038/s41467-019-13500-y

Ejemplares similares