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Lithium alters expression of RNAs in a type-specific manner in differentiated human neuroblastoma neuronal cultures, including specific genes involved in Alzheimer’s disease

Lithium (Li) is a medication long-used to treat bipolar disorder. It is currently under investigation for multiple nervous system disorders, including Alzheimer’s disease (AD). While perturbation of RNA levels by Li has been previously reported, its effects on the whole transcriptome has been given...

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Detalles Bibliográficos
Autores principales: Maloney, Bryan, Balaraman, Yokesh, Liu, Yunlong, Chopra, Nipun, Edenberg, Howard J., Kelsoe, John, Nurnberger, John I., Lahiri, Debomoy K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892907/
https://www.ncbi.nlm.nih.gov/pubmed/31797941
http://dx.doi.org/10.1038/s41598-019-54076-3