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Renewed proliferation in adult mouse cochlea and regeneration of hair cells

The adult mammalian inner ear lacks the capacity to divide or regenerate. Damage to inner ear generally leads to permanent hearing loss in humans. Here, we present that reprogramming of the adult inner ear induces renewed proliferation and regeneration of inner ear cell types. Co-activation of cell...

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Detalles Bibliográficos
Autores principales: Shu, Yilai, Li, Wenyan, Huang, Mingqian, Quan, Yi-Zhou, Scheffer, Deborah, Tian, Chunjie, Tao, Yong, Liu, Xuezhong, Hochedlinger, Konrad, Indzhykulian, Artur A., Wang, Zhengmin, Li, Huawei, Chen, Zheng-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892913/
https://www.ncbi.nlm.nih.gov/pubmed/31797926
http://dx.doi.org/10.1038/s41467-019-13157-7