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Investigation of the preservation effect of canagliflozin on pancreatic beta cell mass using SPECT/CT imaging with (111)In-labeled exendin-4

Radiolabeled exendin derivatives are promising for non-invasive quantification of pancreatic beta cell mass (BCM); longitudinal observation of BCM for evaluation of therapeutic effects has not been achieved. The aim of this study is to demonstrate the usefulness of our developing method using [Lys(1...

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Detalles Bibliográficos
Autores principales: Hamamatsu, Keita, Fujimoto, Hiroyuki, Fujita, Naotaka, Murakami, Takaaki, Shiotani, Masaharu, Toyoda, Kentaro, Inagaki, Nobuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893013/
https://www.ncbi.nlm.nih.gov/pubmed/31797889
http://dx.doi.org/10.1038/s41598-019-54722-w