Telomere analysis using 3D fluorescence microscopy suggests mammalian telomere clustering in hTERT-immortalized Hs68 fibroblasts

Telomere length and dynamics are central to understanding cell aging, genomic instability and cancer. Currently, there are limited guidelines for analyzing telomeric features in 3D using different cellular models. Image processing for telomere analysis is of increasing interest in many fields, howev...

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Detalles Bibliográficos
Autores principales: Adam, Nancy, Degelman, Erin, Briggs, Sophie, Wazen, Rima-Marie, Colarusso, Pina, Riabowol, Karl, Beattie, Tara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893014/
https://www.ncbi.nlm.nih.gov/pubmed/31815205
http://dx.doi.org/10.1038/s42003-019-0692-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893014/
https://www.ncbi.nlm.nih.gov/pubmed/31815205
http://dx.doi.org/10.1038/s42003-019-0692-z

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