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Telomere analysis using 3D fluorescence microscopy suggests mammalian telomere clustering in hTERT-immortalized Hs68 fibroblasts
Telomere length and dynamics are central to understanding cell aging, genomic instability and cancer. Currently, there are limited guidelines for analyzing telomeric features in 3D using different cellular models. Image processing for telomere analysis is of increasing interest in many fields, howev...
Autores principales: | Adam, Nancy, Degelman, Erin, Briggs, Sophie, Wazen, Rima-Marie, Colarusso, Pina, Riabowol, Karl, Beattie, Tara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893014/ https://www.ncbi.nlm.nih.gov/pubmed/31815205 http://dx.doi.org/10.1038/s42003-019-0692-z |
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