Hydrophobic ligands influence the structure, stability, and processing of the major cockroach allergen Bla g 1

The cockroach allergen Bla g 1 forms a novel fold consisting of 12 amphipathic alpha-helices enclosing an exceptionally large hydrophobic cavity which was previously demonstrated to bind a variety of lipids. Since lipid-dependent immunoactivity is observed in numerous allergens, understanding the st...

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Detalles Bibliográficos
Autores principales: Foo, Alexander C. Y., Thompson, Peter M., Perera, Lalith, Arora, Simrat, DeRose, Eugene F., Williams, Jason, Mueller, Geoffrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893020/
https://www.ncbi.nlm.nih.gov/pubmed/31797892
http://dx.doi.org/10.1038/s41598-019-54689-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893020/
https://www.ncbi.nlm.nih.gov/pubmed/31797892
http://dx.doi.org/10.1038/s41598-019-54689-8

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