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Hydrophobic ligands influence the structure, stability, and processing of the major cockroach allergen Bla g 1
The cockroach allergen Bla g 1 forms a novel fold consisting of 12 amphipathic alpha-helices enclosing an exceptionally large hydrophobic cavity which was previously demonstrated to bind a variety of lipids. Since lipid-dependent immunoactivity is observed in numerous allergens, understanding the st...
Autores principales: | Foo, Alexander C. Y., Thompson, Peter M., Perera, Lalith, Arora, Simrat, DeRose, Eugene F., Williams, Jason, Mueller, Geoffrey A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893020/ https://www.ncbi.nlm.nih.gov/pubmed/31797892 http://dx.doi.org/10.1038/s41598-019-54689-8 |
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