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High-throughput sequencing of the transcriptome and chromatin accessibility in the same cell
Single-cell RNA sequencing can reveal the transcriptional state of cells, yet provides little insight into the upstream regulatory landscape associated with open or accessible chromatin regions. Joint profiling of accessible chromatin and RNA within the same cells would permit direct matching of tra...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893138/ https://www.ncbi.nlm.nih.gov/pubmed/31611697 http://dx.doi.org/10.1038/s41587-019-0290-0 |