Endoplasmic reticulum Ca(2+) release causes Rieske iron–sulfur protein-mediated mitochondrial ROS generation in pulmonary artery smooth muscle cells

Mitochondrial reactive oxygen species (ROS) cause Ca(2+) release from the endoplasmic reticulum (ER) via ryanodine receptors (RyRs) in pulmonary artery smooth muscle cells (PASMCs), playing an essential role in hypoxic pulmonary vasoconstriction (HPV). Here we tested a novel hypothesis that hypoxia-...

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Detalles Bibliográficos
Autores principales: Dong, Dapeng, Hao, Qiongyu, Zhang, Ping, Wang, Tao, Han, Fei, Liang, Xiaodong, Fei, Zhenghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Signaling
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893167/
https://www.ncbi.nlm.nih.gov/pubmed/31710081
http://dx.doi.org/10.1042/BSR20192414

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893167/
https://www.ncbi.nlm.nih.gov/pubmed/31710081
http://dx.doi.org/10.1042/BSR20192414

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