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Accurate Allele Frequencies from Ultra-low Coverage Pool-Seq Samples in Evolve-and-Resequence Experiments

Evolve-and-resequence (E+R) experiments leverage next-generation sequencing technology to track the allele frequency dynamics of populations as they evolve. While previous work has shown that adaptive alleles can be detected by comparing frequency trajectories from many replicate populations, this p...

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Detalles Bibliográficos
Autores principales: Tilk, Susanne, Bergland, Alan, Goodman, Aaron, Schmidt, Paul, Petrov, Dmitri, Greenblum, Sharon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893198/
https://www.ncbi.nlm.nih.gov/pubmed/31636085
http://dx.doi.org/10.1534/g3.119.400755