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Accurate Allele Frequencies from Ultra-low Coverage Pool-Seq Samples in Evolve-and-Resequence Experiments
Evolve-and-resequence (E+R) experiments leverage next-generation sequencing technology to track the allele frequency dynamics of populations as they evolve. While previous work has shown that adaptive alleles can be detected by comparing frequency trajectories from many replicate populations, this p...
Autores principales: | Tilk, Susanne, Bergland, Alan, Goodman, Aaron, Schmidt, Paul, Petrov, Dmitri, Greenblum, Sharon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893198/ https://www.ncbi.nlm.nih.gov/pubmed/31636085 http://dx.doi.org/10.1534/g3.119.400755 |
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