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Sex and Individual Differences in Alcohol Intake Are Associated with Differences in Ketamine Self-Administration Behaviors and Nucleus Accumbens Dendritic Spine Density
Clinical and preclinical studies have shown that ketamine, an NMDA receptor antagonist, has promising therapeutic value for the treatment of alcohol use disorder (AUD). However, the maintenance of remission will ultimately require repeated infusions of ketamine, which may lead to abuse potential and...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893233/ https://www.ncbi.nlm.nih.gov/pubmed/31740575 http://dx.doi.org/10.1523/ENEURO.0221-19.2019 |