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SUMOylated SNF2PH promotes variant surface glycoprotein expression in bloodstream trypanosomes

SUMOylation is a post‐translational modification that positively regulates monoallelic expression of the trypanosome variant surface glycoprotein (VSG). The presence of a highly SUMOylated focus associated with the nuclear body, where the VSG gene is transcribed, further suggests an important role o...

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Detalles Bibliográficos
Autores principales: Saura, Andreu, Iribarren, Paula A, Rojas‐Barros, Domingo, Bart, Jean M, López‐Farfán, Diana, Andrés‐León, Eduardo, Vidal‐Cobo, Isabel, Boehm, Cordula, Alvarez, Vanina E, Field, Mark C, Navarro, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893287/
https://www.ncbi.nlm.nih.gov/pubmed/31693280
http://dx.doi.org/10.15252/embr.201948029