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Caspase‐11 counteracts mitochondrial ROS‐mediated clearance of Staphylococcus aureus in macrophages

Methicillin‐resistant Staphylococcus aureus (MRSA) is a growing health concern due to increasing resistance to antibiotics. As a facultative intracellular pathogen, MRSA is capable of persisting within professional phagocytes including macrophages. Here, we identify a role for CASP11 in facilitating...

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Detalles Bibliográficos
Autores principales: Krause, Kathrin, Daily, Kylene, Estfanous, Shady, Hamilton, Kaitlin, Badr, Asmaa, Abu Khweek, Arwa, Hegazi, Rana, Anne, Midhun NK, Klamer, Brett, Zhang, Xiaoli, Gavrilin, Mikhail A, Pancholi, Vijay, Amer, Amal O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893291/
https://www.ncbi.nlm.nih.gov/pubmed/31637841
http://dx.doi.org/10.15252/embr.201948109