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Combined Omics Reveals That Disruption of the Selenocysteine Lyase Gene Affects Amino Acid Pathways in Mice

Selenium is a nonmetal trace element that is critical for several redox reactions and utilized to produce the amino acid selenocysteine (Sec), which can be incorporated into selenoproteins. Selenocysteine lyase (SCL) is an enzyme which decomposes Sec into selenide and alanine, releasing the selenide...

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Detalles Bibliográficos
Autores principales: Seale, Lucia A., Khadka, Vedbar S., Menor, Mark, Xie, Guoxiang, Watanabe, Ligia M., Sasuclark, Alexandru, Guirguis, Kyrillos, Ha, Herena Y., Hashimoto, Ann C., Peplowska, Karolina, Tiirikainen, Maarit, Jia, Wei, Berry, Marla J., Deng, Youping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893568/
https://www.ncbi.nlm.nih.gov/pubmed/31717805
http://dx.doi.org/10.3390/nu11112584