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Transmissibility versus Pathogenicity of Self-Propagating Protein Aggregates

The prion-like spreading and accumulation of specific protein aggregates appear to be central to the pathogenesis of many human diseases, including Alzheimer’s and Parkinson’s. Accumulating evidence indicates that inoculation of tissue extracts from diseased individuals into suitable experimental an...

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Detalles Bibliográficos
Autores principales: Caughey, Byron, Kraus, Allison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893620/
https://www.ncbi.nlm.nih.gov/pubmed/31717531
http://dx.doi.org/10.3390/v11111044