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Npro of Classical Swine Fever Virus Suppresses Type III Interferon Production by Inhibiting IRF1 Expression and Its Nuclear Translocation

Classical swine fever virus (CSFV) causes a contagious disease of pigs. The virus can break the mucosal barrier to establish its infection. Type III interferons (IFN-λs) play a crucial role in maintaining the antiviral state in epithelial cells. Limited information is available on whether or how CSF...

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Detalles Bibliográficos
Autores principales: Cao, Tong, Li, Xiaoye, Xu, Yonghao, Zhang, Shengnan, Wang, Zuohuan, Shan, Ying, Sun, Jianhe, Fang, Weihuan, Li, Xiaoliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893713/
https://www.ncbi.nlm.nih.gov/pubmed/31683525
http://dx.doi.org/10.3390/v11110998