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RAD52 Functions in Homologous Recombination and Its Importance on Genomic Integrity Maintenance and Cancer Therapy

Genomes are continually subjected to DNA damage whether they are induced from intrinsic physiological processes or extrinsic agents. Double-stranded breaks (DSBs) are the most injurious type of DNA damage, being induced by ionizing radiation (IR) and cytotoxic agents used in cancer treatment. The fa...

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Detalles Bibliográficos
Autores principales: Nogueira, Augusto, Fernandes, Mara, Catarino, Raquel, Medeiros, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893724/
https://www.ncbi.nlm.nih.gov/pubmed/31652722
http://dx.doi.org/10.3390/cancers11111622