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The Role of Merlin/NF2 Loss in Meningioma Biology

Mutations in the neurofibromin 2 (NF2) gene were among the first genetic alterations implicated in meningioma tumorigenesis, based on analysis of neurofibromatosis type 2 (NF2) patients who not only develop vestibular schwannomas but later have a high incidence of meningiomas. The NF2 gene product,...

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Detalles Bibliográficos
Autores principales: Lee, Sungho, Karas, Patrick J., Hadley, Caroline C., Bayley V, James C., Khan, A. Basit, Jalali, Ali, Sweeney, Alex D., Klisch, Tiemo J., Patel, Akash J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893739/
https://www.ncbi.nlm.nih.gov/pubmed/31652973
http://dx.doi.org/10.3390/cancers11111633