A Single Point Mutation in the Mumps V Protein Alters Targeting of the Cellular STAT Pathways Resulting in Virus Attenuation

Mumps virus (MuV) is a neurotropic non-segmented, negative-stranded, enveloped RNA virus in the Paramyxovirus family. The 15.4 kb genome encodes seven genes, including the V/P, which encodes, among other proteins, the V protein. The MuV V protein has been shown to target the cellular signal transduc...

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Detalles Bibliográficos
Autores principales: Malik, Tahir, Ngo, Laurie, Bosma, Trent, Rubin, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893744/
https://www.ncbi.nlm.nih.gov/pubmed/31683999
http://dx.doi.org/10.3390/v11111016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893744/
https://www.ncbi.nlm.nih.gov/pubmed/31683999
http://dx.doi.org/10.3390/v11111016

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