Cargando…
A Single Point Mutation in the Mumps V Protein Alters Targeting of the Cellular STAT Pathways Resulting in Virus Attenuation
Mumps virus (MuV) is a neurotropic non-segmented, negative-stranded, enveloped RNA virus in the Paramyxovirus family. The 15.4 kb genome encodes seven genes, including the V/P, which encodes, among other proteins, the V protein. The MuV V protein has been shown to target the cellular signal transduc...
Autores principales: | Malik, Tahir, Ngo, Laurie, Bosma, Trent, Rubin, Steven |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893744/ https://www.ncbi.nlm.nih.gov/pubmed/31683999 http://dx.doi.org/10.3390/v11111016 |
Ejemplares similares
-
Mumps Antibody Response in Young Adults After a Third Dose of Measles-Mumps-Rubella Vaccine
por: Fiebelkorn, Amy Parker, et al.
Publicado: (2014) -
1339 Measles and Mumps Antibody Response in Young Adults after a Third Dose of Measles-Mumps-Rubella Vaccine
por: Fiebelkorn, Amy Parker, et al.
Publicado: (2014) -
Mumps
Publicado: (1908) -
Mumps
Publicado: (1915) -
Interaction of mumps virus V protein variants with STAT1-STAT2 heterodimer: experimental and theoretical studies
por: Rosas-Murrieta, Nora H, et al.
Publicado: (2010)