Zika Virus Non-Structural Protein NS5 Inhibits the RIG-I Pathway and Interferon Lambda 1 Promoter Activation by Targeting IKK Epsilon

The Zika virus (ZIKV) is a member of the Flaviviridae family and an important human pathogen. Most pathogenic viruses encode proteins that interfere with the activation of host innate immune responses. Like other flaviviruses, ZIKV interferes with the expression of interferon (IFN) genes and inhibit...

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Detalles Bibliográficos
Autores principales: Lundberg, Rickard, Melén, Krister, Westenius, Veera, Jiang, Miao, Österlund, Pamela, Khan, Hira, Vapalahti, Olli, Julkunen, Ilkka, Kakkola, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893776/
https://www.ncbi.nlm.nih.gov/pubmed/31690057
http://dx.doi.org/10.3390/v11111024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893776/
https://www.ncbi.nlm.nih.gov/pubmed/31690057
http://dx.doi.org/10.3390/v11111024

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