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Characterization of Brain Inflammation, Apoptosis, Hypoxia, Blood-Brain Barrier Integrity and Metabolism in Venezuelan Equine Encephalitis Virus (VEEV TC-83) Exposed Mice by In Vivo Positron Emission Tomography Imaging

Traditional pathogenesis studies of alphaviruses involves monitoring survival, viremia, and pathogen dissemination via serial necropsies; however, molecular imaging shifts this paradigm and provides a dynamic assessment of pathogen infection. Positron emission tomography (PET) with PET tracers targe...

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Detalles Bibliográficos
Autores principales: Bocan, Thomas M., Stafford, Robert G., Brown, Jennifer L., Akuoku Frimpong, Justice, Basuli, Falguni, Hollidge, Bradley S., Zhang, Xiang, Raju, Natarajan, Swenson, Rolf E., Smith, Darci R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893841/
https://www.ncbi.nlm.nih.gov/pubmed/31766138
http://dx.doi.org/10.3390/v11111052