Elevated Level of PKMζ Underlies the Excessive Anxiety in an Autism Model

Anxiety affects the life quality of a significant percentage of autism patients. To understand the possible biological basis of this high anxiety level, we used a valproic acid (VPA) model of autism. Anxiety level is significantly higher in VPA-injected mice, at both P35 and P70. In addition, protei...

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Detalles Bibliográficos
Autores principales: Gao, Xiaoli, Zheng, Rui, Ma, Xiaoyan, Gong, Zhiting, Xia, Dan, Zhou, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893886/
https://www.ncbi.nlm.nih.gov/pubmed/31849605
http://dx.doi.org/10.3389/fnmol.2019.00291

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893886/
https://www.ncbi.nlm.nih.gov/pubmed/31849605
http://dx.doi.org/10.3389/fnmol.2019.00291

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