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Abnormal lacuno-canalicular network and negative correlation between serum osteocalcin and Cobb angle indicate abnormal osteocyte function in adolescent idiopathic scoliosis

Adolescent idiopathic scoliosis (AIS) is a prevalent spinal deformity occurring during peripubertal growth period that affects 1–4% of adolescents globally without clear etiopathogenetic mechanism. Low bone mineral density is an independent and significant prognostic factor for curve progression. Cu...

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Detalles Bibliográficos
Autores principales: Chen, Huanxiong, Zhang, Jiajun, Wang, Yujia, Cheuk, Ka-Yee, Hung, Alec L. H., Lam, Tsz-Ping, Qiu, Yong, Feng, Jian Q., Lee, Wayne Y. W., Cheng, Jack C. Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894095/
https://www.ncbi.nlm.nih.gov/pubmed/31626573
http://dx.doi.org/10.1096/fj.201901227R