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Epigenetic silencing of the ANKRD26 gene correlates to the pro-inflammatory profile and increased cardio-metabolic risk factors in human obesity

BACKGROUND: Obesity is a major worldwide threat to human health. Increasing evidence indicates that epigenetic modifications have a major impact on the natural history of this disorder. Ankyrin Repeat Domain 26 (Ankrd26) is involved in the development of both obesity and diabetes in mice and is modu...

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Detalles Bibliográficos
Autores principales: Desiderio, Antonella, Longo, Michele, Parrillo, Luca, Campitelli, Michele, Cacace, Giuseppe, de Simone, Sonia, Spinelli, Rosa, Zatterale, Federica, Cabaro, Serena, Dolce, Pasquale, Formisano, Pietro, Milone, Marco, Miele, Claudia, Beguinot, Francesco, Raciti, Gregory A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894277/
https://www.ncbi.nlm.nih.gov/pubmed/31801613
http://dx.doi.org/10.1186/s13148-019-0768-0