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Development and clinical applications of cancer immunotherapy against PD-1 signaling pathway

Dramatic advances in immune therapy have emerged as a promising strategy in cancer therapeutics. In addition to chemotherapy and radiotherapy, inhibitors targeting immune-checkpoint molecules such as cytotoxic T-lymphocyte antigen-4 (CTLA-4), programmed cell death receptor-1 (PD-1) and its ligand (P...

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Detalles Bibliográficos
Autores principales: Wakabayashi, Grace, Lee, Yu-Ching, Luh, Frank, Kuo, Chun-Nan, Chang, Wei-Chao, Yen, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894306/
https://www.ncbi.nlm.nih.gov/pubmed/31801525
http://dx.doi.org/10.1186/s12929-019-0588-8