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Adult human cardiac stem cell supplementation effectively increases contractile function and maturation in human engineered cardiac tissues

BACKGROUND: Delivery of stem cells to the failing heart is a promising therapeutic strategy. However, the improvement in cardiac function in animal studies has not fully translated to humans. To help bridge the gap between species, we investigated the effects of adult human cardiac stem cells (hCSCs...

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Detalles Bibliográficos
Autores principales: Murphy, Jack F., Mayourian, Joshua, Stillitano, Francesca, Munawar, Sadek, Broughton, Kathleen M., Agullo-Pascual, Esperanza, Sussman, Mark A., Hajjar, Roger J., Costa, Kevin D., Turnbull, Irene C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894319/
https://www.ncbi.nlm.nih.gov/pubmed/31801634
http://dx.doi.org/10.1186/s13287-019-1486-4