Immune repertoire fingerprinting by principal component analysis reveals shared features in subject groups with common exposures

BACKGROUND: Advances in next-generation sequencing (NGS) of antibody repertoires have led to an explosion in B cell receptor sequence data from donors with many different disease states. These data have the potential to detect patterns of immune response across populations. However, to this point it...

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Detalles Bibliográficos
Autores principales: Sevy, Alexander M., Soto, Cinque, Bombardi, Robin G., Meiler, Jens, Crowe, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894320/
https://www.ncbi.nlm.nih.gov/pubmed/31801472
http://dx.doi.org/10.1186/s12859-019-3281-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894320/
https://www.ncbi.nlm.nih.gov/pubmed/31801472
http://dx.doi.org/10.1186/s12859-019-3281-8

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