Cargando…
Immune repertoire fingerprinting by principal component analysis reveals shared features in subject groups with common exposures
BACKGROUND: Advances in next-generation sequencing (NGS) of antibody repertoires have led to an explosion in B cell receptor sequence data from donors with many different disease states. These data have the potential to detect patterns of immune response across populations. However, to this point it...
Autores principales: | Sevy, Alexander M., Soto, Cinque, Bombardi, Robin G., Meiler, Jens, Crowe, James E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894320/ https://www.ncbi.nlm.nih.gov/pubmed/31801472 http://dx.doi.org/10.1186/s12859-019-3281-8 |
Ejemplares similares
-
Human-likeness of antibody biologics determined by back-translation and comparison with large antibody variable gene repertoires
por: Schmitz, Samuel, et al.
Publicado: (2020) -
High Frequency of Shared Clonotypes in Human T Cell Receptor Repertoires
por: Soto, Cinque, et al.
Publicado: (2020) -
Computational identification of HCV neutralizing antibodies with a common HCDR3 disulfide bond motif in the antibody repertoires of infected individuals
por: Bozhanova, Nina G., et al.
Publicado: (2022) -
Principal component gene set enrichment (PCGSE)
por: Frost, H. Robert, et al.
Publicado: (2015) -
Diverse patterns of antibody variable gene repertoire disruption in patients with amyloid light chain (AL) amyloidosis
por: Chen, Elaine C., et al.
Publicado: (2020)