Cargando…

Detection of the sickle hemoglobin allele using a surface plasmon resonance based biosensor

Sickle Cell Disease (SCD) is a monogenic hereditary blood disorder caused by a single point mutation (β(S)) in the β globin gene resulting in an abnormal hemoglobin (HbS) that can polymerize within the erythrocytes, inducing their characteristic sickle shape. This causes hemolytic anemia and occlusi...

Descripción completa

Detalles Bibliográficos
Autores principales: Breveglieri, Giulia, D’Aversa, Elisabetta, Cosenza, Lucia Carmela, Boutou, Effrossyni, Balassopoulou, Angeliki, Voskaridou, Ersi, Gambari, Roberto, Borgatti, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Sequoia 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894342/
https://www.ncbi.nlm.nih.gov/pubmed/31853166
http://dx.doi.org/10.1016/j.snb.2019.05.081