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Detection of the sickle hemoglobin allele using a surface plasmon resonance based biosensor
Sickle Cell Disease (SCD) is a monogenic hereditary blood disorder caused by a single point mutation (β(S)) in the β globin gene resulting in an abnormal hemoglobin (HbS) that can polymerize within the erythrocytes, inducing their characteristic sickle shape. This causes hemolytic anemia and occlusi...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Sequoia
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894342/ https://www.ncbi.nlm.nih.gov/pubmed/31853166 http://dx.doi.org/10.1016/j.snb.2019.05.081 |