Delayed administration of recombinant plasma gelsolin improves survival in a murine model of severe influenza

Background: Host-derived inflammatory responses contribute to the morbidity and mortality of severe influenza, suggesting that immunomodulatory therapy may improve outcomes. The normally circulating protein, human plasma gelsolin, is available in recombinant form (rhu-pGSN) and has beneficial effect...

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Detalles Bibliográficos
Autores principales: Yang, Zhiping, Bedugnis, Alice, Levinson, Susan, DiNubile, Mark, Stossel, Thomas, Lu, Quan, Kobzik, Lester
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894358/
https://www.ncbi.nlm.nih.gov/pubmed/31824672
http://dx.doi.org/10.12688/f1000research.21082.2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894358/
https://www.ncbi.nlm.nih.gov/pubmed/31824672
http://dx.doi.org/10.12688/f1000research.21082.2

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