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Delayed administration of recombinant plasma gelsolin improves survival in a murine model of severe influenza
Background: Host-derived inflammatory responses contribute to the morbidity and mortality of severe influenza, suggesting that immunomodulatory therapy may improve outcomes. The normally circulating protein, human plasma gelsolin, is available in recombinant form (rhu-pGSN) and has beneficial effect...
Autores principales: | Yang, Zhiping, Bedugnis, Alice, Levinson, Susan, DiNubile, Mark, Stossel, Thomas, Lu, Quan, Kobzik, Lester |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894358/ https://www.ncbi.nlm.nih.gov/pubmed/31824672 http://dx.doi.org/10.12688/f1000research.21082.2 |
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