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PD-1 Signaling Promotes Control of Chronic Viral Infection by Restricting Type-I-Interferon-Mediated Tissue Damage

Immune responses are essential for pathogen elimination but also cause tissue damage, leading to disease or death. However, it is unclear how the host immune system balances control of infection and protection from the collateral tissue damage. Here, we show that PD-1-mediated restriction of immune...

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Detalles Bibliográficos
Autores principales: Raju, Saravanan, Verbaro, Daniel J., Egawa, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894421/
https://www.ncbi.nlm.nih.gov/pubmed/31775026
http://dx.doi.org/10.1016/j.celrep.2019.10.092