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Aspirin inhibits RANKL-induced osteoclast differentiation in dendritic cells by suppressing NF-κB and NFATc1 activation

BACKGROUND: Aspirin has been demonstrated to promote osteoblast-mediated bone formation and inhibit osteoclast (OC)-mediated bone resorption. However, it remains unclear whether aspirin influences other immune cells during bone resorption. Dendritic cells (DCs), the most potent antigen-presenting ce...

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Detalles Bibliográficos
Autores principales: Wu, Lili, Luo, Zhenhua, Liu, Yitong, Jia, Lu, Jiang, Yiyang, Du, Juan, Guo, Lijia, Bai, Yuxing, Liu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894480/
https://www.ncbi.nlm.nih.gov/pubmed/31805984
http://dx.doi.org/10.1186/s13287-019-1500-x