Subtle changes in striatal muscarinic M1 and M4 receptor expression in the DYT1 knock-in mouse model of dystonia

In early-onset generalized torsion dystonia, caused by a GAG deletion in TOR1A (DYT1), enhanced striatal cholinergic activity has been suggested to be critically involved. Previous studies have shown increased acetylcholine levels in the striatum of DYT1 knock-in (KI) mice. Ex vivo data indicated th...

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Detalles Bibliográficos
Autores principales: Richter, Franziska, Klein, Laura, Helmschrodt, Christin, Richter, Angelika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894858/
https://www.ncbi.nlm.nih.gov/pubmed/31805123
http://dx.doi.org/10.1371/journal.pone.0226080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894858/
https://www.ncbi.nlm.nih.gov/pubmed/31805123
http://dx.doi.org/10.1371/journal.pone.0226080

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