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Repurposing the antimalarial pyronaridine tetraphosphate to protect against Ebola virus infection

Recent outbreaks of the Ebola virus (EBOV) have focused attention on the dire need for antivirals to treat these patients. We identified pyronaridine tetraphosphate as a potential candidate as it is an approved drug in the European Union which is currently used in combination with artesunate as a tr...

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Detalles Bibliográficos
Autores principales: Lane, Thomas R., Massey, Christopher, Comer, Jason E., Anantpadma, Manu, Freundlich, Joel S., Davey, Robert A., Madrid, Peter B., Ekins, Sean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894882/
https://www.ncbi.nlm.nih.gov/pubmed/31751347
http://dx.doi.org/10.1371/journal.pntd.0007890