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Local vulnerability and global connectivity jointly shape neurodegenerative disease propagation

It is becoming increasingly clear that brain network organization shapes the course and expression of neurodegenerative diseases. Parkinson disease (PD) is marked by progressive spread of atrophy from the midbrain to subcortical structures and, eventually, to the cerebral cortex. Recent discoveries...

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Detalles Bibliográficos
Autores principales: Zheng, Ying-Qiu, Zhang, Yu, Yau, Yvonne, Zeighami, Yashar, Larcher, Kevin, Misic, Bratislav, Dagher, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894889/
https://www.ncbi.nlm.nih.gov/pubmed/31751329
http://dx.doi.org/10.1371/journal.pbio.3000495