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Local vulnerability and global connectivity jointly shape neurodegenerative disease propagation
It is becoming increasingly clear that brain network organization shapes the course and expression of neurodegenerative diseases. Parkinson disease (PD) is marked by progressive spread of atrophy from the midbrain to subcortical structures and, eventually, to the cerebral cortex. Recent discoveries...
Autores principales: | Zheng, Ying-Qiu, Zhang, Yu, Yau, Yvonne, Zeighami, Yashar, Larcher, Kevin, Misic, Bratislav, Dagher, Alain |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894889/ https://www.ncbi.nlm.nih.gov/pubmed/31751329 http://dx.doi.org/10.1371/journal.pbio.3000495 |
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