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Monocyte-Derived Macrophages Are Necessary for Beta-Adrenergic Receptor-Driven Choroidal Neovascularization Inhibition

PURPOSE: Beta-adrenergic receptor (AR) antagonists, like propranolol, inhibit angiogenesis in multiple ocular conditions through an unknown mechanism. We previously showed that propranolol reduces choroidal neovascularization (CNV) by decreasing interleukin-6 levels. Since macrophages are one of the...

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Detalles Bibliográficos
Autores principales: Droho, Steven, Cuda, Carla M., Perlman, Harris, Lavine, Jeremy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894922/
https://www.ncbi.nlm.nih.gov/pubmed/31800964
http://dx.doi.org/10.1167/iovs.19-28165